Bio Availability and Bio Equivalence


Bioavailability is defined as: the fraction (percentage) of an directed dose of unbothered medicine that reaches the blood stream (systemic circulation). ‘active pharmaceutical ingredient’ (API), to be able to enter the body. However, to obligate a tonic effect, it is not abundant for the active substance to enter the body. The active substance prerequisites to be vacant in the correct dose at the unambiguous site in the body where it has to work. This specific site is referred to as the ‘target site’. Also, the vigorous affluence needs to reach the target site within a certain time, and be available there for a defined time.


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